Trimethoprim

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Trimethoprim is an antibiotic to treat bacterial infections. It is suitable for the treatment of acute urinary and other bacterial infections such as urinary tract infections (UTIs). It is not a treatment for viral infections such as the common cold and flu.

For males, please select 14 tablets.

  • Effective antibiotic
  • Kills the bacteria that causes UTI's
  • Quick relief
  • Genuine medication
  • All drugs sourced in the UK
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A Doctor's Overview

GP and surgeon, Dr Shane Charles (MBBS, MRCS, PgDip SEM) provides a simple explanation of the medication below:

'Trimethoprim is an antibiotic used to treat several bacterial infections, especially those of the urinary tract. '.

If you think Trimethoprim is a treatment that can help you, start an online consultation now for a registered prescriber to review. If treatment is deemed suitable, they can prescribe it, and we can deliver it to you from the comfort of your own home with a range of convenient delivery and payment options for you to choose from. If you have any questions about a medication, you should always consult your doctor with any questions prior to starting treatment, to ensure that it is safe and suitable for you.

Type of drugAntibiotic
Health conditions prescribed forUrinary tract infections (UTIs) such as cystitis
Active Ingredientstrimethoprim
Brand namesMonotrim, Minotrim, Trimogal
Available strengths200mg
Available astablet
Possible side effectsheadaches, nausea, vomiting, mild rashes and itching, diarrhoea
Patient Information LeafletFor more information on the medication please refer to the patient information leaflet for Trimethoprim.

What is Trimethoprim?

Trimethoprim is an antibiotic used to treat various bacterial infections. It works by targeting and eliminating bacteria, making it effective for conditions like cystitis and urinary tract infections (UTIs). It is a not a treatment for viral infections like the common cold and flu. The effectiveness of trimethoprim and other antibiotics will be decrease when used unnecessarily or when overused.

What does Trimethoprim treat?

  • UTIs: It helps alleviate common symptoms such as burning during urination, frequent urination, and abdominal pain.
  • Other Infections: It can also be used to treat chest infections and acne.

Trimethoprim offers a reliable solution for both immediate treatment and long-term management of bacterial infections.

How does Trimethoprim work?

Trimethoprim fights bacterial infections by preventing bacteria from producing folic acid, an essential nutrient they need to grow and multiply. By blocking this process, Trimethoprim helps clear the infection and relieve symptoms.

  • Stops Bacterial Growth: Trimethoprim works by preventing bacteria from making folic acid, which they need to grow and multiply.
  • Treats Infections: By stopping the bacteria from multiplying, it effectively treats the infection.
  • Effective for Susceptible Bacteria: Doctors ensure that the bacteria causing the infection are susceptible to Trimethoprim to ensure it works effectively.

Trimethoprim is a reliable antibiotic that helps clear bacterial infections by stopping the bacteria from growing and spreading.

Patient Information Leaflet

For more information on the prescription medication patients should refer to the  Trimethoprim patient information leaflet.

Usage Advice

Trimethoprim Tablets

  • Taking the Tablet: Swallow Trimethoprim 200mg tablets whole with a glass of water.
  • Duration of Treatment: For acute infections like bacterial cystitis, treatment usually lasts from 3 to 14 days. Always complete the full course, even if you feel better before it ends.
  • Long-term Treatment: For preventing recurrent infections, take the medication regularly at the same time each day to maintain consistent levels in your body for the best effect.

Trimethoprim is effective when taken as directed by your doctor, helping to clear infections and prevent them from coming back.

How long does it take Trimethoprim to work?

Trimethoprim usually starts to relieve symptoms of cystitis within a few days of starting treatment. The full effectiveness depends on how severe and what type of infection you have.

How should I store Trimethoprim 200mg tablets?

Keep Trimethoprim tablets in a cool, dry place below 25°C and out of reach of children. Ensure you do not use them past their expiry date and dispose of any leftover medicine responsibly.

Dosage

Trimethoprim 200mg

  • Typical Dose for Adults and Children Over 12: 200mg twice a day.
  • Long-term Treatment and Prevention: 100mg at night.

Trimethoprim is usually taken twice daily for infections, with a lower dose for long-term prevention.

The dose of this antibiotic depends on your infection, your age, and how well your kidneys work. Elderly people and individuals with kidney problems are typically prescribed lower doses of the medication.

What should I do if I miss a dose?

Missed Dose: If you forget to take a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Side Effects

Common Side Effects

  • Diarrhoea or constipation
  • High potassium levels in the blood (can lead to abnormal heart rhythm)
  • Feeling nauseous or having a headache
  • Skin rashes or hives (urticaria)
  • Anaemia or sore throat
  • Mouth ulcers or thrush

Uncommon Side Effects

  • Severe, watery, or bloody diarrhoea

Serious Side Effects

  • Trouble breathing or chest pain
  • Swelling of the face, lips, tongue, or throat
  • Shock, fainting, or collapse
  • Blistering or peeling skin
  • Inflammation of the pancreas (pancreatitis)

If you notice any rare, serious, or troubling side effects, stop taking Trimethoprim and seek medical help immediately. For a full list of side effects, read the patient information leaflet.

Warnings

Who are Trimethoprim 200mg tablets suitable for?

Trimethoprim is suitable for most people needing treatment for bacterial infections, especially UTIs. However, it should not be used by those who:

  • Are allergic to any of its ingredients
  • Have certain blood disorders
  • Are pregnant
  • Have severe liver disease
  • Are premature babies or babies in their first few weeks of life

Caution is needed if you have:

  • Kidney disease
  • Are undergoing dialysis
  • Have a folic acid deficiency

Always consult your doctor before starting Trimethoprim to ensure it's safe for you.

Can I take Trimethoprim tablets if I am pregnant?

Trimethoprim should not be used during pregnancy. If you are pregnant or planning to become pregnant and have cystitis symptoms, consult your doctor or pharmacist for advice.

Does Trimethoprim interact with other medications?

Trimethoprim can interact with various other medications, including:

  • Epilepsy treatments
  • Malaria medications
  • Antibiotics
  • Heart condition medications
  • Anticoagulants (blood thinners)

Always inform your doctor or pharmacist about any other medications you are taking to ensure Trimethoprim is safe for you to use.

What precautions does Trimethoprim come with?

  • Allergies: Don't take Trimethoprim if you are allergic to any of its ingredients.
  • Health Conditions: Avoid Trimethoprim if you have certain blood disorders, are pregnant, or have severe liver disease.
  • Infants: Not suitable for premature babies or newborns.
  • Kidney Issues: Use with caution if you have kidney disease or are on dialysis.
  • Potassium Levels: Be aware that Trimethoprim can increase potassium levels, especially if you have kidney problems, poorly controlled diabetes, or are taking certain medications.

Always consult your doctor before starting Trimethoprim to ensure it's safe for you.

Trimethoprim FAQs

How long can I take Trimethoprim for?

The duration you can take Trimethoprim 200mg tablets depends on the type and severity of your bacterial infection.

  • Mild Infections: A short course of treatment may be enough.
  • Serious or Complicated Infections: You might need to take Trimethoprim for a longer period to fully clear the infection.

Always follow your doctor's instructions regarding the length of your treatment.

Can I drink alcohol when taking Trimethoprim tablets?

There isn't a specific warning against drinking alcohol while taking Trimethoprim, but it's best to consult your doctor or pharmacist, especially if you're on other medications or have existing health conditions.

Buy Trimethoprim

Buying Trimethoprim Online in the UK

You can safely buy Trimethoprim online at UK Meds. Please note, all requests for supply of prescription medications are subject to an online clinical consultation and the decision to prescribe will be made by a GMC registered doctor.

Trimethoprim Boots

At the time of writing, generic Trimethoprim is not available at Boots. However, should you wish to purchase Trimethoprim, you can do so at UK Meds. Additionally, if you would like to purchase more than one lot of Trimethoprim tablets, you can benefit from further savings at UK Meds.

Trimethoprim Online Alpha XR

At the time of writing, Trimethoprim is available at Alpha XR. However, should you wish to purchase Trimethoprim at a better price, you can do so at UK Meds. Additionally, if you would like to purchase more than one lot of Trimethoprim tablets, you can benefit from further savings at UK Meds.

Author

Content author

Scott Weaver

Medical Content Writer • Bachelor of Arts Degree

Scott is an experienced, skilled content writer dedicated to creating helpful and accessible medical content for UK Meds.

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Medical Reviewer

Medical Reviewer

Thomas Martin

General Practitioner (GP) • MB BCh

Dr. Thomas Martin is a seasoned family medicine doctor, with over 28 years of experience, including 9 years as a GP in Irish government service and emergency out-of-hours care.

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